The group will work with joint venture (JV) partner Marick Real Estate.
The project is expected to cost £200 million.
The building will be a 14 storey 245,000 sq ft office complex with design features including a series of tiered roof gardens.
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Development at 80 Fenchurch Street will include the demolition of an existing buildings on the site in June.
Stuart Keith, Vice President of Private Real Estate at Partners Group, said: "The recent rebound in the UK economy has created a significant supply-demand imbalance in the City of London in terms of Grade A office space, with vacancy levels close to historic lows and rents steadily climbing.
"80 Fenchurch will be perfectly placed in terms of location, timing and quality of build to capitalize on this attractive market opportunity."
(LM)
